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HUB Organoids

The Binding Bias: How Organoids Are Redefining What Matters in ADC Efficacy

The Binding Bias: How Organoids Are Redefining What Matters in ADC Efficacy

Published by HUB Organoids on Oct 13, 2025

Antibody–drug conjugates (ADCs) are designed to bring the precision of targeted therapy together with the potency of cytotoxic payloads. Naturally, much of the focus during ADC development has been on binding - ensuring that the antibody component efficiently and specifically recognizes its antigen ...

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Ask the Expert: Inside the inFOCUS Assay for IBD Drug Discovery

Ask the Expert: Inside the inFOCUS Assay for IBD Drug Discovery

Published by HUB Organoids on May 27, 2025

In this "Ask the Expert" interview, Dr. Javier Frias Aldeguer, Senior ...

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Regulators Embrace Organoids: Inside the FDA’s Shift Away from Animal Model

Regulators Embrace Organoids: Inside the FDA’s Shift Away from Animal Model

Published by HUB Organoids on May 21, 2025

Last week, the FDA announced a transformative shift in drug ...

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Ask the Expert: How can patient-derived organoids accelerate KRAS drug development?

Ask the Expert: How can patient-derived organoids accelerate KRAS drug development?

Published by HUB Organoids on Jul 5, 2024

In this edition of Ask the Expert, featuring Dr. Yasmine Abouleila, ...

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Ask the experts: Revolutionizing Oncology Drug Development with Organoid Technology

Ask the experts: Revolutionizing Oncology Drug Development with Organoid Technology

Published by HUB Organoids on May 7, 2024

This "Ask the Experts" feature delves into the pressing inquiries ...

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A beginner’s guide to Inflammatory Bowel Diseases (IBD)

A beginner’s guide to Inflammatory Bowel Diseases (IBD)

Published by HUB Organoids on Feb 26, 2024

Inflammatory Bowel Disease (IBD) is a complex condition that affects ...

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Decoding adult stem cells: exploring the hallmarks of stemness

Decoding adult stem cells: exploring the hallmarks of stemness

Published by HUB Organoids on Feb 19, 2024

Discover the 6 hallmarks of stemness in adult tissue Mammalian organ ...

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Ask the Experts – organoid & immune cell co-cultures for immunotherapy

Ask the Experts – organoid & immune cell co-cultures for immunotherapy

Published by HUB Organoids on Jun 23, 2023

In this post of our "Ask the Experts" series, we provide ...

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PDO Screen – Patient-derived Organoids meet Cancer Modeling

PDO Screen – Patient-derived Organoids meet Cancer Modeling

Published by HUB Organoids on Mar 21, 2023

Discover how patient-derived organoids can revolutionize oncology ...

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The FDA Modernization Act 2.0: A patient-centric paradigm shift in drug development

The FDA Modernization Act 2.0: A patient-centric paradigm shift in drug development

Published by HUB Organoids on Jan 16, 2023

Explore what the new legislative bill means for the future of ...

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